Campus Drie Eiken
Universiteitsplein 1
2610 Wilrijk
This course is organized by The Belgian society of Pathology and the Working group of Molecular Pathology.
It is mandatory for residents during their training.
An exam will be organized in due course.
Program
DAY 1 - Friday
|
10:00 |
Course introduction |
|
10:10
10:40 |
An introduction to cancer cell genetics/epigenetics
Epigenetics
|
|
11:10 |
Break |
|
11:20
12:00 |
DNA repair and genome integrity DNA mismatch repair – microsatellite instability (IHC vs. PCR vs. NGS) DNA breaks (SSB-DSB; synthetic lethality in HRD) |
|
12:40 |
Lunch |
|
13:30 14:10 |
Signaling pathways in cancer Oncogenes (EGFR-RAS-RAF-PIK3CA) Tumor suppressor genes (p53-PTEN-Rb-CDKN2A-NF) |
|
14:40 15:30 |
An introduction to onco-immunology Basics Biomarkers |
|
16:00 |
End of day 1 |
DAY 2 – Saturday
|
10:00 |
Fluorescence in situ hybridization: practical aspects |
|
10:30 |
Liquid biopsy: introduction and clinical applications |
|
11:00 |
Break |
|
11:10 |
Next generation sequencing General introduction: the basics of NGS |
|
12:00 |
Lunch |
|
12:30 |
NGS data analysis: practical aspects (pre-analytics, variant interpretation theory, tarification rules) |
|
13:50 |
Break |
|
14:00 |
Practical cases: how to solve your problems? |
|
15:00 |
Closure |
|
15:15 |
End |
Practical information
Presentations
The presentations are available till 17 July.
After this date they will be only available in the members aera.
- F1 An introduction to cancer cell genetics - C. Van Campenhout 2 MB
- F2 An introduction to epigenetics - C. Van Campenhout 3 MB
- F3 DNA mismatch repair – microsatellite instability - Martin Martinez 6 MB
- F4 DNA breaks - Martin Martinez 8 MB
- F6 Next generation sequencing basic principles - C. Van Campenhout 7 MB
- F8 Immunohistochemistry and fluorescence in situ hybridization - N. D’Haene 7 MB
- F13 Practical cases: Thyroid Nodules - N. D’Haene 5 MB
- F14 Practical cases - Martin Martinez 827 KB
- N1 Introduction to cancer cell biology -N. Van Roy 3 MB
- N2 An introduction to epigenetics - L. Spans 2 MB
- N3 DNA mismatch repair in cancer abstract.pdf 781 KB
- N3 DNA mismatch repair – microsatellite instability - F. Dedeurwaerdere 5 MB
- n3-esmo-guidelines-2019fddeurw.pdf 225 KB
- n3-msi-review-voor-oncologen-2020-fddeurw.pdf 1 MB
- N5 splicing variants P.-Pauwels 2 MB
- N5 Signaling pathways in cancer - P. Pauwels 3 MB
- N9 Immunohistochemistry and fluorescence in situ hybridization: practical aspects - J. Van Huysse 3 MB
- N10 Liquid biopsy: introduction and clinical applications - P. Pauwels 4 MB